ALDH1a2 Inhibitors

Product Overview

Alternative Name: Inhibitors of Testicular Retinoic Acid Biosynthesis

Description: ALDH1A2 is an enzyme involved in testicular retinoic acid biosynthesis, that if blocked can arrest spermotogenesis. Small molecule inhibitors of ALDH1A2 are being developed as long-term oral, reversible male contraceptives, based on earlier work on bisdichloroacetyldiamines (BDADs).

Updated date: May 30, 2018

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Status

Status Details:
  • Currently conducting preclinical, in vitro, and early-phase animal testing.

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