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The Contraceptive Pipeline Database
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Amphora is a non-hormonal vaginal gel that works by maintaining a low vaginal pH that creates a hostile environment to sperm and bacteria. Amphora uses lactic acid to maintain the acidic pH in the vagina.
July 21, 2016
Active Pharmaceutical Ingredient (API):
Potential Multi-Purpose Technology (MPT):
The Phase III contraceptive clinical trial concluded in 2014. The trial compared the effectiveness of Amphora with FDA-approved Conceptrol, which contains nonoxynol-9.
Amphora is approved by the FDA as a sexual lubricant.
In the Phase III trial, women used Amphora at least one hour before sex. The results from the study will be evaluated to establish a possible longer window.
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