Bisdichloroacetyldiamines (BDADs)

Product Overview

Alternative Name: BDADs

Development Status: Inactive

Target: Male

Mode: Non-hormonal

Delivery Type: Oral

Duration Type: Long-acting

Description: Bisdichloroacetyldiamines (BDADs, e.g. WIN 18,446) were shown to inhibit testicular retinoic acid biosynthesis and complete arrest of spermatogenesis.

Updated date: May 30, 2018

Vertical Tabs


Project Phase: Early Development

Project Stage: Pre-clinical

Began discovery in: 2008

Status Details:
  • Known to cause unpleasant disulfirim reactions when administered with alcohol due to inhibition of ALDH2 (involved in alcohol metabolism in liver), so further development was abandoned.

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