Cu/LDPE Composite IUD

Alternative Name: Nanocomposite Copper (Cu) IUD

Description: A blend of copper and low-density polyethylene (LDPE) nanocomposite material in an IUD shape. The new materials are designed to control the release rate of copper ions, without decreasing the efficacy of the IUD, but reducing the clinical side effects.

Product Details

User: Female

Hormonal: No

Delivery Method: Intrauterine

Duration Type: Long-acting

Duration: 5 years

  • Single insertion

Active Pharmaceutical Ingredient (API):
  • copper

Inactive material: polyethylene

Multipurpose Preventive Technology (MPT): No

Status Details

Developer: Tongji Medical College at Huazhong University of Science and Technology

Project Phase: Limited Market Availability

Development Stage: Marketed

Began discovery in: 2003

Active Development: Yes

Status Details:
  • In 2013, the Cu/LDPE Composite IUD was registered by the Chinese FDA.

Additional Information

  • Product website:

  • Hu XL, et al. (2014) Alterations in the endometrium of rats, rabbits, and Macaca mulatta that received an implantation of copper/low-density polyethylene nanocomposite. International Journal of Nanomedicine. 9:1127-38.

  • Hu XL, et al. (2013) Biological evaluation of the copper/low-density polyethylene nanocomposite intrauterine device. Plos One 8(9):e74128.

  • Yu J,et al. (2008) Comparative study on contraceptive efficacy and clinical performance of the copper/low-density polyethylene nanocom IUD and the copper T220C IUD. Contraception. 78:319-23.

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