Alternative Name: Estetrol (E4) + Drospirenone (DRSP) Combined Pill

Description: 15mg E4 plus 3mg DRSP in an oral contraceptive.

Product Details

User: Female

Hormonal: Yes

Delivery Method: Oral

Duration Type: Short-acting

Duration: One day

Dose: 15 mg E4, 3 mg DRSP

Active Pharmaceutical Ingredient (API):
  • estetrol (E4)
  • drospirenone

Multipurpose Preventive Technology (MPT): No

Status Details

Developer: Mithra

Project Phase: Pre-Clinical and Clinical Development

Development Stage: Phase III

Began discovery in: 2001

Active Development: Yes

Status Details:
  • Ongoing phase III clinical trial on efficacy, safety, and acceptability of 15 mg E4 and 3 mg DRSP in the U.S. and Canada.

Additional Information


  • Pantarhei Bioscience is no longer involved in development.

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