Skip to main content
Enter your The Contraceptive Pipeline Database username.
Enter the password that accompanies your username.
Single dose method of non-surgical male sterilization, administered by injection, which has an effect on murine spermatogenesis. Effect is not permanent, so no further development was pursued.
May 30, 2018
Intended to be permanent, but was reversible on testing
Was intended to be a method of permanent sterilization, but effect was not permanent, so no further development was pursued.
Use of FSHβ as a targeting vector to the testes may permit use of lower dose of melphalan and so reduce potential side effects.
Low-cost technology using available compounds, likely to be inexpensive.
Potential for testicular toxicity such as hypogonadism and/or late testicular neoplasms from the melphalan.
Download Product Report