Levogel
Alternative Name: Pericoital LNG gel
Description: A vaginal gel containing 0.75mg levonorgestrel and potentially a microbicide or an ARV for multipurpose prevention for pericoital use, potentially postcoital.
Product Details
Duration: Single use
Regimen:
Dose: 0.75 mg LNG
Active Pharmaceutical Ingredient (API):
Status Details
Began discovery in: 2001
Status Details: - The Phase I study was completed documenting PK and PD profiles. Further development includes optimization of gel retention for 24h or more, time of application, and impact of action if use is repeated during the same menstrual cycle.
- The Phase I study was completed documenting PK and PD profiles. Further development includes optimization of gel retention for 24h or more, time of application, and impact of action if use is repeated during the same menstrual cycle.
Additional Information
References: Brache V, Croxatto H, et al. (2007) Effect of a single vaginal administration of levonorgestrel in Carraguard gel on the ovulatory process: a potential candidate for "dual protection" emergency contraception. Contraception. 76(2):111-6.
Clinicaltrials.gov Identified NCT01286948
Brache V, Croxatto H, et al. (2007) Effect of a single vaginal administration of levonorgestrel in Carraguard gel on the ovulatory process: a potential candidate for "dual protection" emergency contraception. Contraception. 76(2):111-6.
Clinicaltrials.gov Identified NCT01286948