Na,K-ATPase α4
Description: The α4 polypeptide is a testis-specific isoform of the catalytic sub-unit of the Na,K-ATPase, which is essential for sperm motility and fertility.
Target
Product Details
User: Male
Hormonal: No
Role in reproduction: Sperm Function
Multipurpose Preventive Technology (MPT): No
Status Details
Developer: University of Kansas Medical Center, University of Minnesota
Project Phase: Discovery and Early Development
Development Stage: Target Validation
Active Development: Yes
Additional Information
References: Jimenez T, McDermott JP, et al. (2011) Na,K-ATPase alpha4 isoform is essential for sperm fertility. Proc Natl Acad Sci U S A. 108(2):644-9.
Jimenez T, McDermott JP, et al. (2011) Na,K-ATPase alpha4 isoform is essential for sperm fertility. Proc Natl Acad Sci U S A. 108(2):644-9.