Na,K-ATPase α4

Description: The α4 polypeptide is a testis-specific isoform of the catalytic sub-unit of the Na,K-ATPase, which is essential for sperm motility and fertility.

Target

Product Details

User: Male

Hormonal: No

Role in reproduction: Sperm Function

Multipurpose Preventive Technology (MPT): No

Status Details

Developer: University of Kansas Medical Center, University of Minnesota

Project Phase: Discovery and Early Development

Development Stage: Target Validation

Active Development: Yes

Additional Information

References:
  • Jimenez T, McDermott JP, et al. (2011) Na,K-ATPase alpha4 isoform is essential for sperm fertility. Proc Natl Acad Sci U S A. 108(2):644-9.

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