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NET Pellets
Product Overview
Alternative Name:
Biodegradable Norethindrone (NET) Pellets
Development Status:
Inactive
Target:
Female
Mode:
Hormonal
Delivery Type:
Subdermal
Duration Type:
Long-acting
Description:
Cylindrical biodegradable subcutaneous pellets made of fused cholesterol and norethindrone.
Updated date:
May 30, 2018
Vertical Tabs
Product Details
Active Pharmaceutical Ingredient (API):
norethindrone
Potential Multi-Purpose Technology (MPT):
No
Regimen:
single administration
Duration:
1-3 years
Dose:
125 mg
Partner:
Anterion Therapeutics
,
FHI 360
Status
Project Phase:
Late Development
Project Stage:
Phase II
Status Details:
Anterion Therapeutics has gone out of business.
Programmatic Considerations
Considerations:
Demonstrated efficacy for 2-3 years in Phase II trials, with potential to shorten duration by re-configuring the number and size/shape of the pellets.
Absorbed over time, so do not require removal. Can be removed by a minor surgical procedure, up to a point after which they are too degraded to be removed. Removal takes longer than removal of existing implants.
Additional Information
Footnotes:
See also entry on LNG Pellets.
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