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SPHERA™ Hormonal IUB™
Hormonal Intrauterine Ball
A sustained release flexible carrier containing progesterone is attached to shape-memory alloy wire. The wire is straight when in applicator, and curls into a three-dimensional ball once released from the inserter and into the uterus.
May 30, 2018
Active Pharmaceutical Ingredient (API):
Nitinol (nickel and titanium composite material) wire
Potential Multi-Purpose Technology (MPT):
OCON Medical Ltd.
Began discovery in:
The design aims to reduce uterine perforations and malposition. The ability of the product to compress and expand during cyclic changes of the uterine cavity may help the product find the area of least resistance to minimize side effects.
The insertion tube profile will be relatively small and the product will be supplied pre-loaded.
See also the entry for the copper IUB from OCON.
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