Testicular Ultrasound
Description: Application of therapeutic ultrasound to testes.
Product Details
Duration Type: ,
Duration: 6 months
Regimen:
Status Details
Developer: , , ,
Began discovery in: 1970s
Status Details: - Already tested in multiple species for efficacy, toxicology, and genotoxicity. The method provides permanent sterilization in rats and dogs, but transient contraception in monkeys. Obtaining a long-lasting effect in humans has not yet been found.
- Initial work on this method was conducted in the 1970s at the University of Missouri at Columbia. In 2010, researchers at UNC-Chapel Hill won a grant to study the method in rats. Parsemus Foundation is funding an Italian team who worked on dogs and a team at the University of California who worked on monkeys.
- Already tested in multiple species for efficacy, toxicology, and genotoxicity. The method provides permanent sterilization in rats and dogs, but transient contraception in monkeys. Obtaining a long-lasting effect in humans has not yet been found.
- Initial work on this method was conducted in the 1970s at the University of Missouri at Columbia. In 2010, researchers at UNC-Chapel Hill won a grant to study the method in rats. Parsemus Foundation is funding an Italian team who worked on dogs and a team at the University of California who worked on monkeys.
Additional Information
References: Parsemus Foundation website: http://www.parsemus.org/projects/ultrasound/
VandeVoort CA, Tollner TL. (2012) The efficacy of ultrasound treatment as a reversible male contraceptive in the rhesus monkey. Reprod Biol Endocrinol. 10:81.
Tsuruta JK, Dayton PA, et al. (2012) Therapeutic ultrasound as a potential male contraceptive: power, frequency and temperature required to deplete rat testes of meiotic cells and epididymides of sperm determined using a commercially available system. Reprod Biol Endocrinol. 10:7.
Leoci R, Aiudi G, et al. (2015) Therapeutic ultrasound as a potential male dog contraceptive: determination of the most effective application protocol. Reprod Domest Anim. 50(5):712-8.
Parsemus Foundation website: http://www.parsemus.org/projects/ultrasound/
VandeVoort CA, Tollner TL. (2012) The efficacy of ultrasound treatment as a reversible male contraceptive in the rhesus monkey. Reprod Biol Endocrinol. 10:81.
Tsuruta JK, Dayton PA, et al. (2012) Therapeutic ultrasound as a potential male contraceptive: power, frequency and temperature required to deplete rat testes of meiotic cells and epididymides of sperm determined using a commercially available system. Reprod Biol Endocrinol. 10:7.
Leoci R, Aiudi G, et al. (2015) Therapeutic ultrasound as a potential male dog contraceptive: determination of the most effective application protocol. Reprod Domest Anim. 50(5):712-8.