Androgen Restored Contraceptive

Product Overview

Alternative Name: ARC; triple hormone contraceptive; Triple OC

Development Status: Active Development

Target: Female

Mode: Hormonal

Delivery Type: Oral

Duration Type: Short-acting

Description: Androgen restored contraceptive consists of prasterone, estradiol, and progesterone. By adding the natural human androgen dehydroepiandrosterone (DHEA) to an oral contraceptive (OC), the developers anticipate to minimize subjective side effects such as mood changes, decrease of sexual desire, and risk of venous thromboembolic events. Addition of a suitable formulation and dose of DHEA normalizes testosterone (T) levels during OC use and is expected to counteract the clinical consequences of T-deficiency.

Updated date: May 30, 2018

Vertical Tabs


Project Phase: Late Development

Project Stage: Phase II

Status Details:
  • As of late 2015, the drug is in phase-II/III clinical trials in the Netherlands.
  • The drug has also been in development (clinical phase unknown) in USA for transdermal use.

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