Androgen Restored Contraceptive

Product Overview

Alternative Name: ARC; triple hormone contraceptive; Triple OC

Description: Androgen restored contraceptive consists of prasterone, estradiol, and progesterone. By adding the natural human androgen dehydroepiandrosterone (DHEA) to an oral contraceptive (OC), the developers anticipate to minimize subjective side effects such as mood changes, decrease of sexual desire, and risk of venous thromboembolic events. Addition of a suitable formulation and dose of DHEA normalizes testosterone (T) levels during OC use and is expected to counteract the clinical consequences of T-deficiency.

Updated date: May 30, 2018

Vertical Tabs


Status Details:
  • As of late 2015, the drug is in phase-II/III clinical trials in the Netherlands.
  • The drug has also been in development (clinical phase unknown) in USA for transdermal use.

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