Alternative Name: Nestorone + Ethinyl Estradiol One-Year Contraceptive Vaginal Ring, NES + EE Vaginal Ring

Description: The one-year contraceptive vaginal ring contains ethinyl estradiol (EE) and Nestorone® (NES), in a silicone elastomer ring with 2 cores. It is left in place for 21 days and removed for seven days, for up to 13 cycles (one-year).

Product Details

Duration: One year


Dose: 150µg NES, 15µg EE per day

Active Pharmaceutical Ingredient (API):

Inactive material: silicone elastomer

Status Details

Developer: , , , , , ,

Began discovery in: 1990's

Status Details:
  • In August 2018, the FDA approved the NES +EE vaginal ring with the marketed name of Annovera.
  • The Population Council is pursuing regulatory approval in low and middle-income countries, with funding from their USAID project, Delivering a Family of Contraceptive Vaginal Rings.

Additional Information


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