Anti-Mullerian Hormone (AMH)

Alternative Name: Mullerian-inhibiting Substance (MIS), Mullerian-inhibiting Hormone (MIH), Mullerian-inhibiting Factor (MIF), Mullerian Duct Inhibitory Factor (MDIF), Mullerian Regression Factor (MRF), Anti-paramesonephric Hormone (APH)

Product Details

Multipurpose Preventive Technology (MPT): No

Status Details

Project Phase: Discovery and Early Development

Development Stage: Lead Optimization

Active Development: Yes

Additional Information

References:
  • Woodruff, T. K. (2017). A win-win for women’s reproductive health: A nonsteroidal contraceptive and fertoprotective neoadjuvant.Proceedings of the National Academy of Sciences,114(9), 2101-2102.

  • Visser, J. (2003). AMH signaling: from receptor to target gene.Molecular and Cellular Endocrinology, 211(1-2), pp.65-73.

  • Kano, M., Sosulski, A. E., Zhang, L., Saatcioglu, H. D., Wang, D., Nagykery, N., . . . Pépin, D. (2017). AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy.Proceedings of the National Academy of Sciences,114(9).

  • Durlinger, A. (1999). Control of Primordial Follicle Recruitment by Anti-Mullerian Hormone in the Mouse Ovary.Endocrinology, 140(12), pp.5789-5796.

  • Behringer, R., Finegold, M. and Cate, R. (1994). Müllerian-inhibiting substance function during mammalian sexual development.Cell, 79(3), pp.415-425.

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