Biodegradable Implant with [Poly(PDL-co-DO)] Co-polymers

Alternative Name: LNG Biodegradable Implant for Contraception, Yale BDI

Description: A subcutaneous, biodegradable rod implant that can achieve 18-24 months sustained delivery of LNG using novel [Poly(PDL-co-DO)] co-polymers.

Product Details

User: Female

Hormonal: Yes

Delivery Method: Subdermal

Duration Type: Long-acting

Duration: 18-24 months

Regimen:
  • Single administration every 18-24 months

Active Pharmaceutical Ingredient (API):
  • levonorgestrel

Inactive material: pentadecalactone; dioxanone

Multipurpose Preventive Technology (MPT): No

Status Details

Developer: FHI 360, Yale University

Project Phase: Pre-Clinical and Clinical Development

Development Stage: Pre-clinical

Began discovery in: 2014

Active Development: Yes

Status Details:
  • Rat PK studies have been completed/ongoing. User acceptability studies ongoing.

Additional Information

References:

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