Desogestrel + Testosterone
Description: Combined male contraceptive using desogestrel and testosterone. Pilot work used oral desogestrel and depot testosterone, but further development would likely use a combined depot approach.
Product Details
User: Male
Hormonal: Yes
Delivery Method: Oral, Subdermal
Duration Type: Long-acting
Regimen: - Daily oral desogestrel, testosterone depot every 3 months
- Daily oral desogestrel, testosterone depot every 3 months
Dose: 300mcg desogestrel, 300mg testosterone
Active Pharmaceutical Ingredient (API): - testosterone
- desogestrel
- testosterone
- desogestrel
Multipurpose Preventive Technology (MPT): No
Status Details
Developer: University of Edinburgh
Project Phase: Pre-Clinical and Clinical Development
Development Stage: Phase II
Began discovery in: 1995
Active Development: No
Status Details: - While pilot work showed that this is a promising approach that could be taken further, no further development is currently taking place.
- While pilot work showed that this is a promising approach that could be taken further, no further development is currently taking place.
Additional Information
References: Kinniburgh D, et al. (2002) Oral desogestrel with testosterone pellets induces consistent suppression of spermatogenesis to azoospermia in both Caucasian and Chinese men. Human Reprod. 17:1490-1501.
Kinniburgh D, et al. (2002) Oral desogestrel with testosterone pellets induces consistent suppression of spermatogenesis to azoospermia in both Caucasian and Chinese men. Human Reprod. 17:1490-1501.