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DPV + LNG Vaginal Ring
Dapivirine (DPV) + levonorgestrel (LNG) vaginal ring
A silicone intravaginal ring (IVR) that a woman inserts and leaves in place for 90 days. The ring releases a combination of dapivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI), to prevent HIV and levonorgestrel, a synthetic progestin, to prevent unintended pregnancy.
May 30, 2018
Active Pharmaceutical Ingredient (API):
Potential Multi-Purpose Technology (MPT):
International Partnership for Microbicides
GMP manufacturing of Phase I supplies are ongoing. In collaboration with the NIH-funded Microbicide Trials Network (MTN), a U.S.-based Phase I trial is expected to begin in 2016.
International Partnership for Microbicides website
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