DPV + LNG Vaginal Ring

Product Overview

Alternative Name: Dapivirine (DPV) + levonorgestrel (LNG) vaginal ring

Development Status: Active Development

Target: Female

Mode: Hormonal

Delivery Type: Vaginal Ring

Duration Type: Long-acting

Description: A silicone intravaginal ring (IVR) that a woman inserts and leaves in place for 90 days. The ring releases a combination of dapivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI), to prevent HIV and levonorgestrel, a synthetic progestin, to prevent unintended pregnancy.

Updated date: May 30, 2018

Vertical Tabs


Project Phase: Early Development

Project Stage: Pre-clinical

Status Details:
  • GMP manufacturing of Phase I supplies are ongoing. In collaboration with the NIH-funded Microbicide Trials Network (MTN), a U.S.-based Phase I trial is expected to begin in 2016.

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