DPV + LNG Vaginal Ring

Alternative Name: Dapivirine (DPV) + levonorgestrel (LNG) vaginal ring

Description: A silicone intravaginal ring (IVR) that a woman inserts and leaves in place for 90 days. The ring releases a combination of dapivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI), to prevent HIV and levonorgestrel, a synthetic progestin, to prevent unintended pregnancy.

Product Details

Duration: 90 days

Active Pharmaceutical Ingredient (API):

Inactive material: silicone

Status Details

Developer: ,

Status Details:
  • In collaboration with the NIH-funded Microbicide Trials Network (MTN), a U.S.-based Phase I trial was completed in August, 2017 and another phase I trial is currently underway.

Additional Information

References:

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