GTx C-6

Alternative Name: SARM C-6

Description: (S)-3(4-chloro-3fluorophenoxy)-2-hydroxy-2methyl-N-(4nitro-3-trifluoromethylphenyl) propionamide, or GTx C-6, is a selective androgen receptor modulator (SARM). It is thought to have a combination of activity that inhibits spermatogenesis but maintains sexual function, libido and muscle mass.

Product Details

User: Male

Hormonal: Yes

Delivery Method: Oral

Duration Type: Short-acting

Active Pharmaceutical Ingredient (API):
  • (S)-3(4-chloro-3fluorophenoxy)-2-hydroxy-2methyl-N-(4nitro-3-trifluoromethylphenyl) propionamide [GTx C-6]

Multipurpose Preventive Technology (MPT): No

Status Details

Developer: GTx, Inc., Memphis, TN

Project Phase: Pre-Clinical and Clinical Development

Development Stage: Pre-clinical

Active Development: No

Status Details:
  • Development of the compound as a male contraceptive agent not currently being pursued by GTx.

Additional Information

  • Chen J, Hwang DJ, et al. (2004) A Selective Androgen Receptor Modulator for Hormonal Male Contraception. Journal of Pharmacology and Experimental Therapeutics. 312(2).

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