Description: A non-hormonal emergency contraceptive option. It is a cyclooxygenase-2 (COX-2) inhibitor that blocks ovulation. Dosing is 30 mg for 5 days. Meloxicam is marketed as a nonsteroidal, anti-inflammatory agent used for pain.

Product Details

User: Female

Hormonal: No

Delivery Method: Oral

Duration Type: Emergency

Duration: 5 days

  • Taken after unprotected intercourse for 5 days

Dose: 30 mg (per day)

Active Pharmaceutical Ingredient (API):
  • meloxicam

Multipurpose Preventive Technology (MPT): No

Status Details

Developer: CONRAD

Project Phase: Pre-Clinical and Clinical Development

Development Stage: Phase II

Active Development: Yes

Status Details:
  • A Phase II trial (led by CONRAD) in Santiago, Chile tested the safety and efficacy of 2 different doses of meloxicam, 15 mg and 30 mg, taken daily for 5 days for the prevention of ovulation. Findings indicate that the 30 mg dose is safe and effective and may offer an alternative to hormonal emergency contraception.

Additional Information

  • CONRAD website:

  • Identified NCT01346137

  • Jesem C, et al. (2014) Effect of oral administration of a continuous 18 day regimen of meloxicam on ovulation: experience of a randomized controlled trial. Contraception. 90(2); 168-73.

  • McCann NC, et al. (2013) The COX-2 inhibitor meloxicam prevents pregnancy when administered as an emergency contraceptive to nonhuman primates. Contraception. 88(6):744-8.

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