MENT Implant

Alternative Name: MENT Acetate Implant

Description: MENT is a synthetic androgen that resembles testosterone. MENT binds to androgen receptor with greater binding affinity than testosterone and dihydrotestosterone, the two active endogenous androgens. The higher bioactivity allows a reduced dose compared to testosterone for daily use. Four MENT Acetate (MENT Ac) implants delivering 1200-1600 µg of MENT Ac/day for 1 year.

Product Details

User: Male

Hormonal: Yes

Delivery Method: Subdermal

Duration Type: Long-acting

Duration: One year

  • 4 implants replaced after one year

Dose: 1200-1600 µg (per day)

Active Pharmaceutical Ingredient (API):
  • 7alpha-Methyl-19-Nortestosterone

Inactive material: elastomer; EVA

Multipurpose Preventive Technology (MPT): No

Status Details

Developer: Population Council

Project Phase: Pre-Clinical and Clinical Development

Development Stage: Phase II

Began discovery in: 1990

Active Development: Yes

Status Details:
  • Four MENT Ac implants were not totally efficacious in men. MENT Ac implants in combination with DMPA injections are being investigated for synergy in efficacy to induce azoospermia.

Additional Information


  • See also entry on MENT Gel.

Vertical Tabs