NES + E2 Vaginal Ring
Alternative Name: Nestorone (NES) + Estradiol (E2) Vaginal Ring
Description: Vaginal ring that delivers Nestorone (NES) and Estradiol (E2) for 3 consecutive months.
Product Details
Duration: 3 months
Regimen:
Dose: Nestorone 200mcg/d; E2 TBD
Active Pharmaceutical Ingredient (API):
Inactive material: silicone elastomer
Status Details
Developer: ,
Began discovery in: 2011
Status Details: - A Phase II trial has begun to evaluate the efficacy and safety of the product.
- A Phase II trial has begun to evaluate the efficacy and safety of the product.
Additional Information
References: Jensen JT, et al. (2018) Continuous dosing of a novel contraceptive vaginal ring releasing Nestorone® and estradiol: pharmacokinetics from a dose-finding study. Contraception. 97(5); 422-427.
NICHD Website: https://www.nichd.nih.gov/about/org/diphr/officebranch/cdp/research/cont...
Clinicaltrials.gov Identified NCT03432416
Jensen JT, et al. (2018) Continuous dosing of a novel contraceptive vaginal ring releasing Nestorone® and estradiol: pharmacokinetics from a dose-finding study. Contraception. 97(5); 422-427.
NICHD Website: https://www.nichd.nih.gov/about/org/diphr/officebranch/cdp/research/cont...
Clinicaltrials.gov Identified NCT03432416