Nutlin-3a
Description: Treatment of nutlin-3a led to decreased expression of ubiquinol-cytochrome-c reductase core protein 2 (UQCRC2) and tyrosine phosphorylation (TYP) proteins, leading to reduced fertility.
Product Details
User: ,
Delivery Method: , ,
Duration Type: ,
Status Details
Additional Information
References: Atatreh, N., Ghattas, M. A., Bardaweel, S. K., Rawashdeh, S. A., & Sorkhy, M. A. (2018). Identification of new inhibitors of Mdm2–p53 interaction via pharmacophore and structure-based virtual screening.Drug Design, Development and Therapy,Volume 12, 3741-3752.
Shukla, K. K., Kwon, W., Rahman, M. S., Park, Y., You, Y., & Pang, M. (2013). Nutlin-3a Decreases Male Fertility via UQCRC2.PLoS ONE,8(10).
Atatreh, N., Ghattas, M. A., Bardaweel, S. K., Rawashdeh, S. A., & Sorkhy, M. A. (2018). Identification of new inhibitors of Mdm2–p53 interaction via pharmacophore and structure-based virtual screening.Drug Design, Development and Therapy,Volume 12, 3741-3752.
Shukla, K. K., Kwon, W., Rahman, M. S., Park, Y., You, Y., & Pang, M. (2013). Nutlin-3a Decreases Male Fertility via UQCRC2.PLoS ONE,8(10).