Tamsulosin
Alternative Name: Flomax
Description: Tamsulosin is an FDA approved medication for the treatment of benign prostatic hyperplasia, with a listed side effect of ejaculatory disfunction. It is an α1A-adrenoreceptor antagonist; these receptors are found in the neck of the bladder, seminal vesicles, and vas deferens.
Product Details
Regimen:
Dose: FDA labeled for 0.4 mg
Active Pharmaceutical Ingredient (API):
Status Details
Additional Information
References: FDA Label: https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/020579s016lbl.pdf
Hellstrom, W. J., & Sikka, S. C. (2006). Effects of Acute Treatment with Tamsulosin Versus Alfuzosin on Ejaculatory Function in Normal Volunteers.The Journal of Urology,176(4), 1529-1533.
Hellstrom, W. J., & Sikka, S. C. (2009). Effects of Alfuzosin and Tamsulosin on Sperm Parameters in Healthy Men: Results of aShort-Term, Randomized, Double-Blind, Placebo-Controlled, Crossover Study.Journal of Andrology,30(4), 469-474.
Sanbe, A., Tanaka, Y., Fujiwara, Y., Tsumura, H., Yamauchi, J., Cotecchia, S., . . . Tanoue, A. (2009). α1-Adrenoceptors are required for normal male sexual function.British Journal of Pharmacology,152(3), 332-340.
Wang, J., Zhao, Y., Jiang, S., Xia, Q., Wei, C., Wang, M., . . . Jin, X. (2012). Assessment of Tamsulosin as a Potential Male Contraceptive in Healthy Volunteers.Urology,80(3), 614-617.
White, C. W., Choong, Y., Short, J. L., Exintaris, B., Malone, D. T.,Allen, A. M., . . . Ventura, S. (2013). Male contraception via simultaneous knockout of 1A-adrenoceptors and P2X1-purinoceptors in mice.Proceedings of the National Academy of Sciences,110(51), 20825-20830.
FDA Label: https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/020579s016lbl.pdf
Hellstrom, W. J., & Sikka, S. C. (2006). Effects of Acute Treatment with Tamsulosin Versus Alfuzosin on Ejaculatory Function in Normal Volunteers.The Journal of Urology,176(4), 1529-1533.
Hellstrom, W. J., & Sikka, S. C. (2009). Effects of Alfuzosin and Tamsulosin on Sperm Parameters in Healthy Men: Results of aShort-Term, Randomized, Double-Blind, Placebo-Controlled, Crossover Study.Journal of Andrology,30(4), 469-474.
Sanbe, A., Tanaka, Y., Fujiwara, Y., Tsumura, H., Yamauchi, J., Cotecchia, S., . . . Tanoue, A. (2009). α1-Adrenoceptors are required for normal male sexual function.British Journal of Pharmacology,152(3), 332-340.
Wang, J., Zhao, Y., Jiang, S., Xia, Q., Wei, C., Wang, M., . . . Jin, X. (2012). Assessment of Tamsulosin as a Potential Male Contraceptive in Healthy Volunteers.Urology,80(3), 614-617.
White, C. W., Choong, Y., Short, J. L., Exintaris, B., Malone, D. T.,Allen, A. M., . . . Ventura, S. (2013). Male contraception via simultaneous knockout of 1A-adrenoceptors and P2X1-purinoceptors in mice.Proceedings of the National Academy of Sciences,110(51), 20825-20830.