Vasalgel

Alternative Name: Vas deferens polymer contraceptive

Description: A polymer gel is injected into the vas deferens blocking the sperm. Vasalgel is a long-term method that can be used indefinitely, but that is more easily reversible than vasectomy.

Product Details

User: Male

Hormonal: No

Delivery Method: Vas Deferens

Duration Type: Permanent, Long-acting

Duration: Indefinite

Regimen:
  • single administration

Multipurpose Preventive Technology (MPT): No

Status Details

Developer: Parsemus Foundation

Project Phase: Pre-Clinical and Clinical Development

Development Stage: Pre-clinical

Began discovery in: 2010

Active Development: Yes

Status Details:
  • Successful pre-clinical studies in rabbits, baboons and dogs have been completed. Phase I clinical studies are expected to start in 2018.

Additional Information

References:
  • Parsemus Foundation website: http://www.parsemusfoundation.org/projects/vasalgel/

  • Colagross-Schouten, A., Lemoy, M., Keesler, R. I., Lissner, E., & Vandevoort, C. A. (2017). The contraceptive efficacy of intravas injection of Vasalgelâ„¢ for adult male rhesus monkeys.Basic and Clinical Andrology,27(1).

  • Khourdaji, I., Zillioux, J., Eisenfrats, K., Foley, D., & Smith, R. (2018). The future of male contraception: A fertile ground.Translational Andrology and Urology,7(S2).

  • Waller, D., Bolick,D., Lissner,E., Premanandan, C., & Gamerman, G. (2016). Azoospermia in rabbits following an intravas injection of Vasalgelâ„¢. Basic and Clinical Andrology, 26(6).

  • Waller, D., Bolick, D., Lissner, E., Premanandan, C., & Gamerman, G. (2017). Reversibility of Vasalgelâ„¢ male contraceptive in a rabbit model.Basic and Clinical Andrology,27(1).

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